The Skinny Confidential Him & Her Show

The Glucose Goddess Jessie Inchauspé On The Truth About Blood Sugar, Energy, & Managing Cravings

March 9, 2026

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  • The order in which food is eaten significantly impacts the blood sugar response, with eating vegetables first, followed by proteins/fats, and then starches resulting in a much smaller glucose spike. 
  • A mother's diet during pregnancy directly shapes the physical and brain development of her baby, making prenatal nutrition critical for long-term health outcomes. 
  • Glucose spikes cause inflammation, contribute to fat gain, and accelerate aging, while the subsequent glucose crash leads to cravings, fatigue, and hunger. 
  • Maternal nutrition during pregnancy, specifically adequate intake of choline, protein, and omega-3s, has a scientifically proven, measurable, and long-term impact on a child's brain development and intelligence. 
  • The misconception that pregnancy is a 'free-for-all' or that the baby will automatically get what it needs from the mother is false; diet consciousness during pregnancy is crucial. 
  • Managing glucose levels is not just about avoiding sugar but is fundamental because steady glucose prevents fat storage mode and reduces cravings, often leading to weight loss as a beneficial side effect of overall health improvement. 

Segments

Intro and Guest Background
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(00:00:25)
  • Key Takeaway: Jessie Inchauspé is the Glucose Goddess, author of ‘Glucose Revolution’ and ‘The Glucose Goddess Method’.
  • Summary: The hosts introduce Jessie Inchauspé, highlighting her background as a French biochemist and her focus on translating science into easy tips for blood sugar management.
Eating Healthy: France vs. US
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(00:01:31)
  • Key Takeaway: Eating healthy is cheaper and easier in France than in the US, requiring more strategy when visiting the US.
  • Summary: Jessie discusses the cultural differences in accessing healthy food, noting that in France, fresh, healthy options are the baseline, whereas in the US, it requires more planning and expense.
Craziest Glucose Finding: Food Order
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(00:03:15)
  • Key Takeaway: The order you eat food matters: veggies first slow down the glucose spike from carbs.
  • Summary: Jessie shares that eating vegetables before proteins/fats, and then starches, significantly reduces the blood sugar response due to fiber creating a protective mesh.
Pregnancy Diet Shapes Baby
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(00:04:21)
  • Key Takeaway: Maternal diet during pregnancy co-creates the baby’s body and brain setup, impacting future health and IQ.
  • Summary: Jessie explains how nutrients like choline and Omega-3s, or lack thereof due to high sugar intake, lead to measurable differences in a toddler’s brain development and metabolic vulnerability.
What is Glucose and Spikes?
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(00:08:08)
  • Key Takeaway: Glucose is energy; too much causes inflammation, fat gain, and aging; spikes lead to crashes and cravings.
  • Summary: Glucose is defined as the body’s energy source from carbs/sugars. Too much arriving rapidly (a spike) causes negative consequences like inflammation and weight gain, followed by a crash.
Glucose Monitoring and Adaptation
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(00:10:53)
  • Key Takeaway: Monitoring glucose provides real-time insight to adapt behavior, such as taking a walk after an unexpected spike.
  • Summary: Jessie explains she wears a CGM about 70% of the time to learn how different foods and behaviors affect her levels instantly.
Best Glucose Dinner Strategy
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(00:16:33)
  • Key Takeaway: A glucose-friendly dinner involves a veggie starter, followed by protein, and then carbs (like pasta) for dessert.
  • Summary: Jessie outlines her ideal dinner structure: roasted broccoli starter, followed by meat/turkey, and then pasta, with fruit for dessert.
Vinegar Lowers Glucose Spike
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(00:17:31)
  • Key Takeaway: Drinking a tablespoon of vinegar in water before eating carbs can lower the glucose spike by up to 40%.
  • Summary: Vinegar contains a molecule that slows down how quickly carbs turn into glucose in the digestive system.
Origin Story: Back Injury & Mental Health
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(00:27:15)
  • Key Takeaway: Jessie discovered the link between high glucose spikes and her severe depersonalization episodes after breaking her back.
  • Summary: Jessie details how, after a severe accident, she found that wearing a glucose monitor revealed that eating sugary foods like a donut triggered her debilitating mental health symptoms.
Controlling vs. Being Controlled by Donuts
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(00:33:12)
  • Key Takeaway: The goal is not deprivation, but strategy: eat treats like donuts after a meal to avoid starting the day on a glucose roller coaster.
  • Summary: Jessie emphasizes that having a donut for breakfast starts a cycle of cravings, whereas having it as dessert after a balanced meal allows you to control the food, not the other way around.